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PF-04634817 (succinate) [2140301-98-8]

HY-117621A
MedChem Express
CAS Number2140301-98-8
Product group Chemicals
Estimated Purity99.50
Molecular Weight629.67
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PF-04634817 (succinate) [2140301-98-8]
  • Delivery Days Customer
    10
  • CAS Number
    2140301-98-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.50
  • Molecular Formula
    C29H42F3N5O7
  • Molecular Weight
    629.67
  • Scientific Description
    PF-0463481 succinate is a potent and orally active dual CCR2/CCR5 antagonist with comparable human and rodent CCR2 potency (rat IC50=20.8 nM), and displays 10-20 fold less rodent CCR5 potency (rat IC50=470 nM). PF-0463481 succinate is safe and well-tolerated and has the potential for the study of diabetic nephropathy[3].
  • SMILES
    O=C(N1[C@@]2([H])C[C@@]([H])(C1)N(C3=NC=NC(C(F)(F)F)=C3)C2)[C@@]4(C[C@@H](CC4)N[C@@H]5[C@@H](COCC5)OC)C(C)C.OC(CCC(O)=O)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200