PF-04691502

Biorbyt

PF-04691502

16

1013101-36-4

Research Use Only

C22H27N5O4

425.48

PF-04691502 is an ATP-competitive PI3K(alpha/beta/delta/gamma)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK.

O=C1C(C2=CC=C(OC)N=C2)=CC3=C(C)N=C(N)N=C3N1[C@H]4CC[C@H](OCCO)CC4

12352200