PF-04802367 [1962178-27-3]

TargetMol Chemicals

PF-04802367 [1962178-27-3]

4

1962178-27-3

Chemical

Research Use Only

PF-04802367

C16H16ClN5O3

361.78

PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3beta enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and potency. It is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3alpha and GSK-3beta) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively.

3 years

COc1ccc(cc1Cl)-c1ocnc1C(=O)NCCCn1cncn1

-20°C

12352200