PF-04859989 (hydrochloride) [177943-33-8]

MedChem Express

PF-04859989 (hydrochloride) [177943-33-8]

10

177943-33-8

Research Use Only

99.90

C9H11ClN2O2

214.65

PF-04859989 hydrochloride is a brain-penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC50s of 23 and 263 nM for hKAT II and rKAT II. PF-04859989 hydrochloride is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 microM, respectively)[1].

O=C1N(O)C2=C(C=CC=C2)C[C@@H]1N.[H]Cl

2°C to 8°C

12352200