PF-05020182 [1354712-92-7]
HY-108327
CAS Number1354712-92-7
Product group Chemicals
Molecular Weight366.46
Overview
- SupplierMedChem Express
- Product NamePF-05020182 [1354712-92-7]
- Delivery Days Customer5
- CAS Number1354712-92-7
- CertificationResearch Use Only
- Molecular FormulaC18H30N4O4
- Molecular Weight366.46
- Scientific DescriptionPF-05020182 is an orally active opener for Kv7 channel, that activates human Kv7.2/7.3, Kv7.4 and Kv7.3/7.5 with EC50 of 334, 625 and 588 nM, respectively. PF-05020182 exhibits anticonvulsant activity in rats corneal electric shock-induced tonic seizure (MES) models. PF-05020182 is blood-brain barrier (BBB) penetrable[1].
- SMILESO=C(CC(C)(C)C)NC1=C(OC)N=C(N2CCC(CC2)OC)N=C1OC
- UNSPSC12352200