PF-05387252 [1604034-71-0]

MedChem Express

PF-05387252 [1604034-71-0]

9

1604034-71-0

Research Use Only

C25H27N5O2

429.51

PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified[1].

N#CC1=CC2=C(C=C1)C3=C(C4=CC(OC)=C(C=C4N=C3)OCCCN5CCN(CC5)C)N2

12352200