PF-06250112

MedChem Express

PF-06250112 [1609465-89-5]

10

1609465-89-5

Research Use Only

C22H20F2N6O2

438.43

PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC 50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC 50 s of 0.9 nM and 1.2 nM, respectively [1] .

O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N

12352200