PF-06250112 [1609465-89-5]

MedChem Express

PF-06250112 [1609465-89-5]

10

1609465-89-5

Research Use Only

C22H20F2N6O2

438.43

PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively[1].

O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N

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