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PF-06372222 [1407592-99-7]

PF-06372222 [1407592-99-7]

T24620
TargetMol Chemicals
Molecular Weight515.53
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PF-06372222 [1407592-99-7]
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PF-06372222
  • Molecular Formula
    C26H28F3N5O3
  • Molecular Weight
    515.53
  • Scientific Description
    PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR). PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.
  • Shelf life instruction
    3 years
  • SMILES
    [C@@H](NC=1C=CC(=NC1)N2C=C(C(F)(F)F)N=C2)(C3CC(C)(C)C3)C4=CC=C(C(NCCC(O)=O)=O)C=C4
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Song G et al., 2017 Jun 8, Nature
    Read more