PF-06463922 acetate [1924207-18-0]

TargetMol Chemicals

PF-06463922 acetate [1924207-18-0]

114

Research Use Only

PF-06463922 acetate

C23H23FN6O4

466.4734

PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non-small cell lung cancer (NSCLC).

3 years

CC(O)=O.C[C@H]1Oc2cc(cnc2N)-c2c(CN(C)C(=O)c3ccc(F)cc13)nn(C)c2C#N

-20°C

12352200