PF-06648671

MedChem Express

PF-06648671 [1587727-31-8]

10

1587727-31-8

Research Use Only

98.05

C25H23ClF4N4O3

538.92

PF-06648671 is a novel, brain-penetrable, and orally active gamma-secretase modulator (GSM). PF-06648671 reduces Abeta42 and Abeta40, with concomitant increases in Abeta37 and Abeta38 in vitro. PF-06648671 is used for the study of Alzheimers disease[1].

FC(F)(C(C=C1Cl)=C([C@](CC2)([H])O[C@]2([H])[C@@H](N(CCN3C4=CC=C(N5C=NC(C)=C5)C3=O)C4=O)C)C=C1F)F

-20°C

12352200