PF-06815345 [1900686-46-5]
HY-112598
CAS Number1900686-46-5
Product group Chemicals
Molecular Weight598.03
Overview
- SupplierMedChem Express
- Product NamePF-06815345 [1900686-46-5]
- Delivery Days Customer10
- CAS Number1900686-46-5
- CertificationResearch Use Only
- Molecular FormulaC27H29ClFN9O4
- Molecular Weight598.03
- Scientific DescriptionPF-06815345 is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 microM. PF-06815345 significantly decreases the PCSK9 level in vivo in mouse[1][2].
- SMILESO=C(N([C@H]1CNCCC1)C2=C(Cl)C=CC=N2)C3=CC=C(C4=C(C5=NN=NN5[C@H](C)OC(OCC)=O)N(C)N=C4)C(F)=C3
- UNSPSC12352200