PF-184

MedChem Express

PF-184

10

Research Use Only

C32H32ClFN6O4

619.09

PF-184 is a potent and selective IKK-2 inhibitor ( IC 50 : 37 nM) over rhIKK-1, IKKi, and more than 30 tyrosine and serine/threonine kinases. PF-184 can be used in the research of inflammation, such as asthma and chronic obstructive pulmonary disease [1] .

O=C(C1=NN(C2=C1CCC3=C2C=C(NC(C4=CC(N5C[C@](CO)([C@](CO)(C5)C)C)=NC=C4Cl)=O)C=C3)C6=CC=C(C=C6)F)N

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