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PF-3845

HY-14380
MedChem Express
CAS Number1196109-52-0
Product group Chemicals
Estimated Purity99.95
Molecular Weight456.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PF-3845 [1196109-52-0]
  • Delivery Days Customer
    10
  • CAS Number
    1196109-52-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C24H23F3N4O2
  • Molecular Weight
    456.46
  • Scientific Description
    PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH) , with a K i of 0.23 microM. PF-3845 is a covalent inhibitor that carbamylates FAAHs serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition [1] [3] .
  • SMILES
    O=C(N1CCC(CC2=CC=CC(OC3=NC=C(C=C3)C(F)(F)F)=C2)CC1)NC4=CN=CC=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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