PF-4136309 [1341224-83-6]

MedChem Express

PF-4136309 [1341224-83-6]

10

1341224-83-6

Research Use Only

99.86

C29H31F3N6O3

568.59

PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.

O[C@]1(CC[C@](CC1)([H])N[C@@H]2CN(CC2)C(CNC(C3=CC=CC(C(F)(F)F)=C3)=O)=O)C4=NC=C(C=C4)C5=NC=CC=N5

-20°C,2°C to 8°C

12352200