PF-4191834 [1029317-21-2]

MedChem Express

PF-4191834 [1029317-21-2]

10

1029317-21-2

Research Use Only

99.77

C22H23N3O2S

393.50

PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes, and is effective in inflammation and pain[1].

O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N

-20°C,2°C to 8°C

12352200