PF-431396

MedChem Express

PF-431396 [717906-29-1]

10

717906-29-1

Research Use Only

99.13

C22H21F3N6O3S

506.50

PF-431396 is an orally active dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor, with IC 50 values of 2 nM and 11 nM, respectively [1] [2] [3] [4] .

CS(=O)(N(C)C1=CC=CC=C1CNC2=NC(NC3=CC4=C(C=C3)NC(C4)=O)=NC=C2C(F)(F)F)=O

-20°C,2°C to 8°C

12352200