PF-4708671

AbMole BioScience

PF-4708671

9

1255517-76-0

Chemical

Research Use Only

C19H21F3N6

390.41

PF-4708671 is a novel cell-permeable inhibitor of S6K1 with Ki/IC50 value of 20 nM/160 nM. PF4708671 inhibits MSK1 (IC50 of 0.95 uM) 4-fold more weakly than S6K1.

CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C([NH]3)C=CC(=C4)C(F)(F)F

12352200