PF-514273 [851728-60-4]

MedChem Express

PF-514273 [851728-60-4]

5

851728-60-4

Research Use Only

C21H17Cl2F2N3O2

452.28

PF-514273 is an orally active, selective antagonist for cannabinoid-1 receptor (CB1) with IC50 of 1 nM. PF-514273 reduces the food uptake in mice, and can be used for obesity research[1].

O=C1N(CC(F)(F)C)CCOC2=C(C3=CC=C(Cl)C=C3)N(C4=CC=CC=C4Cl)N=C12

12352200