PF-6683324 [1799788-94-5]

MedChem Express

PF-6683324 [1799788-94-5]

10

1799788-94-5

Research Use Only

99.41

C24H23F4N5O4

521.46

PF-6683324 (Trk-IN-4) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1].

O=C(N)C1=C(O[C@H]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[C@H]2F)N=CC(C4=CN(C)C=N4)=C1

-20°C,2°C to 8°C

12352200