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PF-8380 [1144035-53-9]

PF-8380 [1144035-53-9]

T3631
TargetMol Chemicals
CAS Number1144035-53-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.45%
Molecular Weight478.33
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PF-8380 [1144035-53-9]
  • Delivery Days Customer
    4
  • CAS Number
    1144035-53-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PF-8380
  • Estimated Purity
    99.45%
  • Molecular Formula
    C22H21Cl2N3O5
  • Molecular Weight
    478.33
  • Scientific Description
    PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at the site of inflammation.
  • Shelf life instruction
    3 years
  • SMILES
    Clc1cc(Cl)cc(COC(=O)N2CCN(CCC(=O)c3ccc4[nH]c(=O)oc4c3)CC2)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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