PFI-2 [1627676-59-8]
HY-18627
CAS Number1627676-59-8
Product group Chemicals
Molecular Weight499.52
Overview
- SupplierMedChem Express
- Product NamePFI-2 [1627676-59-8]
- Delivery Days Customer10
- CAS Number1627676-59-8
- CertificationResearch Use Only
- Molecular FormulaC23H25F4N3O3S
- Molecular Weight499.52
- Scientific DescriptionPFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 microM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis[1][2].
- SMILESO=S(C1=CC2=C(CNCC2)C(F)=C1)(N[C@H](CC3=CC=CC(C(F)(F)F)=C3)C(N4CCCC4)=O)=O
- UNSPSC12352200
![PFI-2 [1627676-59-8] [1627676-59-8]](https://www.targetmol.com/group3/M00/02/6B/CgoaEWY7LU-ESvvYAAAAAJf4kJE021.png)