PFI-7-O-C4-piperazin
HY-174997
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NamePFI-7-O-C4-piperazin
- Delivery Days Customer999
- CertificationResearch Use Only
- Molecular FormulaC31H41N7O2
- Molecular Weight543.70
- Scientific DescriptionPFI-7-O-C4-piperazin is a E3 ligase ligand-linker conjugate that can be used for synthesis of PROTACs, such as NEP162 (HY-174996). The E3 ligase ligand (PFI-7) of NEP162 is a highly selective antagonist of GID4 (KD = 0.22 microM). NEP162 is a BRD4 PROTAC degrader with anti-tumor activity[1].
- SMILESO=C(N[C@@H]1CC[C@H](C2=NC(C=CC(OCCCN3CCNCC3)=C4)=C4N2)CC1)CNCC(N5)=CC6=C5C=CC=C6
- UNSPSC41115800