PFKFB3 Polyclonal Antibody
RD219543A
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Rat
TargetPFKFB3
Overview
- SupplierReddot Biotech
- Product NamePFKFB3 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.9 mg/ml
- ConjugateUnconjugated
- Gene ID5209
- Target namePFKFB3
- Target description6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
- Target synonymsIPFK2, PFK2, iPFK-2, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase, 6PF-2-K/Fru-2,6-P2ase 3, 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme, PFK/FBPase 3, fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase, inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, renal carcinoma antigen NY-REN-56
- HostRabbit
- IsotypeIgG
- Protein IDQ16875
- Protein Name6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
- Scientific DescriptionThe protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. - This is a PFKFB3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- ReactivityHuman, Rat
- Storage Instruction-20°C
- UNSPSC41116161





![PFKFB3 antibody [C3], C-term detects PFKFB3 protein at nucleus on BT483 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded BT483 xenograft. PFKFB3 antibody [C3], C-term (GTX108335) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min](https://www.genetex.com/upload/website/prouct_img/normal/GTX108335/GTX108335_39834_IHC_w_23060120_226.webp)