PFM01

Biorbyt

PFM01 [1558598-41-6]

10

1558598-41-6

Research Use Only

C14H15NO2S2

293.399

PFM01 (SML1735) is a small molecule that specifically inhibits endonuclease, but not exonuclease activity of MRE11, inhibits dsDNA end resection in A549 cells with IC50 of 50-75 uM, blocks the ssDNA-binding path toward the catalytic metal ions and disrupt

S1/C(=C\C2=CC=C(O)C=C2)/C(=O)N(CC(C)C)C1=S

12352200