PFN2 Polyclonal Antibody

Reddot Biotech

PFN2 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

PFN2

profilin 2

D3S1319E; PFL; profilin II; profilin-2

Rabbit

IgG

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Human, Mouse, Rat

-20°C

12352203