
WB analysis of human skeletal muscle lysate using GTX89046 PGC1 alpha antibody, Internal. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
PGC1 alpha antibody, Internal
GTX89046
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPARGC1A
Overview
- SupplierGeneTex
- Product NamePGC1 alpha antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.3-1 microg/mL. ICC/IF: 10 microg/mL. IHC-P: 6-8 microg/mL. FACS: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID10891
- Target namePPARGC1A
- Target descriptionPPARG coactivator 1 alpha
- Target synonymsLEM6; ligand effect modulator-6; L-PGC-1alpha; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC1; PGC-1(alpha); PGC1A; PGC-1alpha; PGC-1-alpha; PGC-1v; PPAR gamma coactivator variant form; PPARgamma coactivator 1alpha; PPARGC1; PPARGC-1-alpha
- HostGoat
- IsotypeIgG
- Protein IDQ9UBK2
- Protein NamePeroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Scientific DescriptionThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity. Lau WK et al., 2019 Sep 5, BMC Complement Altern MedRead more
- Late-onset caloric restriction alters skeletal muscle metabolism by modulating pyruvate metabolism. Chen CN et al., 2015 Jun 1, Am J Physiol Endocrinol MetabRead more