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WB analysis of human skeletal muscle lysate using GTX89046 PGC1 alpha antibody, Internal. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human skeletal muscle lysate using GTX89046 PGC1 alpha antibody, Internal. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human skeletal muscle lysate using GTX89046 PGC1 alpha antibody, Internal. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer

PGC1 alpha antibody, Internal

GTX89046
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPARGC1A
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Overview

  • Supplier
    GeneTex
  • Product Name
    PGC1 alpha antibody, Internal
  • Delivery Days Customer
    7
  • Application Supplier Note
    WB: 0.3-1 microg/mL. ICC/IF: 10 microg/mL. IHC-P: 6-8 microg/mL. FACS: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10891
  • Target name
    PPARGC1A
  • Target description
    PPARG coactivator 1 alpha
  • Target synonyms
    LEM6; ligand effect modulator-6; L-PGC-1alpha; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC1; PGC-1(alpha); PGC1A; PGC-1alpha; PGC-1-alpha; PGC-1v; PPAR gamma coactivator variant form; PPARgamma coactivator 1alpha; PPARGC1; PPARGC-1-alpha
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDQ9UBK2
  • Protein Name
    Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • Scientific Description
    The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity. Lau WK et al., 2019 Sep 5, BMC Complement Altern Med
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  • Late-onset caloric restriction alters skeletal muscle metabolism by modulating pyruvate metabolism. Chen CN et al., 2015 Jun 1, Am J Physiol Endocrinol Metab
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