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PHA-543613

HY-105670
MedChem Express
CAS Number478149-53-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.95
Molecular Weight271.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PHA-543613 [478149-53-0]
  • Delivery Days Customer
    10
  • CAS Number
    478149-53-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C15H17N3O2
  • Molecular Weight
    271.32
  • Scientific Description
    PHA-543613 is a potent, orally active, brain-penetrant and selective alpha7 nAChR agonist with a K i of 8.8 nM. PHA-543613 displays selectivity for alpha7-nAChR over alpha3beta4, alpha1beta1gammadelta, alpha4beta2 and 5-HT3 receptors [1] . PHA-543613 can be used for the cognitive deficits of Alzheimers disease and schizophrenia research [2] .
  • SMILES
    O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200