Phelorphan [110871-16-4]
HY-114939
CAS Number110871-16-4
Product group Chemicals
Molecular Weight386.46
Overview
- SupplierMedChem Express
- Product NamePhelorphan [110871-16-4]
- Delivery Days Customer9
- CAS Number110871-16-4
- CertificationResearch Use Only
- Molecular FormulaC20H22N2O4S
- Molecular Weight386.46
- Scientific DescriptionPhelorphan is a purine MTH1 inhibitor identified through chemical array screening. Although it targets cellular MTH1, its cytotoxicity to cancer cells is weaker than that of other reported inhibitors. The cytotoxicity of MTH1 inhibitors may be attributed to off-target effects, and MTH1 is not essential for cancer cell survival.
- SMILESO=C([C@@H](NC([C@@H](NC(CS)=O)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)O
- UNSPSC12352200