Phenformin [114-86-3]

MedChem Express

Phenformin [114-86-3]

14

114-86-3

Research Use Only

99.72

C10H15N5

205.26

Phenformin (1-phenethylbiguanide) is an orally active antidiabetic and anticancer agent. Phenformin has an incidence of associated lactic acidosis. Phenformin acts through acting AMPK activation and blocking mTOR pathway. Phenformin is also a substrate of P-glycoprotein (P-gp), and an OXPHOS inhibitor. Phenformin induces cancer cell apoptosis[1][2].

NC(NC(NCCC1=CC=CC=C1)=N)=N

RT

12352200