Phenoxodiol

MedChem Express

Phenoxodiol [81267-65-4]

10

81267-65-4

Research Use Only

99.89

C15H12O3

240.25

Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis . Phenoxodiol also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21 WAF1 via a p53 independent manner [1] [2] .

OC1=CC=C2C=C(C3=CC=C(O)C=C3)COC2=C1

-20°C,2°C to 8°C

12352200