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PHKA1 antibody [C2C3], C-term

Research Use Only
GTX109401
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPHKA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PHKA1 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5255
  • Target name
    PHKA1
  • Target description
    phosphorylase kinase regulatory subunit alpha 1
  • Target synonyms
    PHKA; phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform; phosphorylase kinase alpha M subunit; phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP46020
  • Protein Name
    Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
  • Scientific Description
    The PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 2.7.1.38), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB; MIM 172490), and gamma (PHKG1; MIM 172470 and PHKG2; MIM 172471) subunits have several isoforms; the delta subunit is calmodulin (CALM1; MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome.[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Enhancement of anaerobic glycolysis - a role of PGC-1alpha4 in resistance exercise. Koh JH et al., 2022 Apr 28, Nat Commun
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  • PGC-1alpha mediates a rapid, exercise-induced downregulation of glycogenolysis in rat skeletal muscle. Kim SH et al., 2015 Feb 1, J Physiol
    Read more