PHKA1 antibody [C2C3], C-term
GTX109401
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPHKA1
Overview
- SupplierGeneTex
- Product NamePHKA1 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5255
- Target namePHKA1
- Target descriptionphosphorylase kinase regulatory subunit alpha 1
- Target synonymsPHKA, phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform, phosphorylase kinase alpha M subunit, phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis
- HostRabbit
- IsotypeIgG
- Protein IDP46020
- Protein NamePhosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
- Scientific DescriptionThe PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 2.7.1.38), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB; MIM 172490), and gamma (PHKG1; MIM 172470 and PHKG2; MIM 172471) subunits have several isoforms; the delta subunit is calmodulin (CALM1; MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome.[supplied by OMIM]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Koh JH, Pataky MW, Dasari S, et al. Enhancement of anaerobic glycolysis - a role of PGC-1α4 in resistance exercise. Nat Commun. 2022,13(1):2324. doi: 10.1038/s41467-022-30056-6Read this paper
- Kim SH, Koh JH, Higashida K, et al. PGC-1α mediates a rapid, exercise-induced downregulation of glycogenolysis in rat skeletal muscle. J Physiol. 2015,593(3):635-43. doi: 10.1113/jphysiol.2014.283820Read this paper




