Phloxine B [18472-87-2]

TargetMol Chemicals

Phloxine B [18472-87-2]

44

18472-87-2

Chemical

Research Use Only

Phloxine B

C20H2Br4Cl4Na2O5

829.63

Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics. It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positive bacteria. At 100 microg/ml, it can inhibit methicillin-resistant S. aureus growth in vitro. Phloxine B has also been shown to modulate channel activity of wild-type cystic fibrosis transmembrane conductance regulator chloride channels (CFTR; Ki = 38 microM) and mutant delta F508 CFTR (Ki = 33 microM).

3 years

[Na].Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C22OC(=O)c3c2c(Cl)c(Cl)c(Cl)c3Cl)c1Br

-20°C

12352200