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Phosphatidylglycerols (egg) (sodium salt) [383907-64-0]

HY-W251428
MedChem Express
CAS Number383907-64-0
Product group Chemicals
Estimated Purity99.92
Molecular Weight783.04
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Phosphatidylglycerols (egg) (sodium salt) [383907-64-0]
  • Delivery Days Customer
    10
  • CAS Number
    383907-64-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C42H80NaO9P
  • Molecular Weight
    783.04
  • Scientific Description
    Phosphatidylglycerols (PG) is a selective inhibitor targeting the TLR4 accessory protein CD14/MD-2 complex, inhibiting LPS or virus (such as RSV)-mediated inflammatory signaling pathways through competitive binding. Phosphatidylglycerols directly bind to viral particles to block infection, inhibit COX-2 expression to reduce the release of inflammatory factors (IL-6, IL-8), and improve oxidative stress by regulating mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols can be taken orally or by inhalation and can be used in the study of chronic inflammatory diseases (such as atherosclerosis) and respiratory viral infections (such as RSV)[1][2][3].
  • SMILES
    CCCCCCCCCCCCCCCC(OC[C@](CC(CCCCCCC/C=C\CCCCCCCC)=O)(C)COP(OCC(O)CO)(O[Na])=O)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200