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Western Blot analysis of HepG2 cells using Phospho-AKT1 (Thr308) Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of HepG2 cells using Phospho-AKT1 (Thr308) Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of HepG2 cells using Phospho-AKT1 (Thr308) Polyclonal Antibody at dilution of 1:1000

Phospho-Akt (T308) Polyclonal Antibody

Research Use Only
E-AB-21082
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    Phospho-Akt (T308) Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    WB,ELISA
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Scientific Description
    The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
  • UNSPSC
    12352203