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Western blot analysis of extracts from Hela cells treated with serum using BTK (phospho-Tyr223) Antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from Hela cells treated with serum using BTK (phospho-Tyr223) Antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from Hela cells treated with serum using BTK (phospho-Tyr223) Antibody.The lane on the right is treated with the antigen-specific peptide.

Phospho-BTK (Tyr223) Antibody

CSB-PA142166
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBTK
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Overview

  • Supplier
    Cusabio
  • Product Name
    Phospho-BTK (Tyr223) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID695
  • Target name
    BTK
  • Target description
    Bruton tyrosine kinase
  • Target synonyms
    agammaglobulinaemia tyrosine kinase; AGMX1; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton's tyrosine kinase; dominant-negative kinase-deficient Brutons tyrosine kinase; IGHD3; IMD1; PSCTK1; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; XLA
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ06187
  • Protein Name
    Tyrosine-protein kinase BTK
  • Scientific Description
    Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. Sulekha Verma, J. Biol. Chem., Feb 2001; 276: 4671 - 4676. Yan M. Li, Cancer Res., Nov 2003; 63: 7630 - 7633. Malti Nikrad, Mol. Cancer Ther., Mar 2005; 4: 443 - 449. Feng Dong, Infect. Immun., Mar 2005; 73: 1861 - 1864. Hiroo Ueno, Mol. Biol. Cell, Feb 2
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203