Western Blot analysis of COS-7 cells with Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody
Phospho-IkappaB-alpha (S32/S36) Polyclonal Antibody
E-AB-20911
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePhospho-IkappaB-alpha (S32/S36) Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierWB,IHC,IF,ELISA
- CertificationResearch Use Only
- Concentration1 mg/ml
- Scientific DescriptionInhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
- UNSPSC12352203