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Western blot analysis of extracts from NIH-3T3 tissue using MAP3K7 (Phospho-Thr187) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from NIH-3T3 tissue using MAP3K7 (Phospho-Thr187) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from NIH-3T3 tissue using MAP3K7 (Phospho-Thr187) antibody.The lane on the right is treated with the antigen-specific peptide.

Phospho-MAP3K7 (Thr187) Antibody

Research Use Only
CSB-PA089775
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetMAP3K7
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Overview

  • Supplier
    Cusabio
  • Product Name
    Phospho-MAP3K7 (Thr187) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID6885
  • Target name
    MAP3K7
  • Target description
    mitogen-activated protein kinase kinase kinase 7
  • Target synonyms
    CSCF; FMD2; MEKK7; mitogen-activated protein kinase kinase kinase 7; TAK1; TGF1a; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43318
  • Protein Name
    Mitogen-activated protein kinase kinase kinase 7
  • Scientific Description
    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. Shin MS, et al. (2009)Biochim Biophys Acta 1793, 1156-64 Liu Q, Busby JC, Molkentin JD (2009)Nat Cell Biol 11, 154-61 Kim SI, Kwak JH, Wang L, Choi ME (2008)J Biol Chem 283, 10753-63
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203