Western Blot analysis of A549 cells using Phospho-p70 S6 kinase alpha (Ser447) Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of A549 cells using Phospho-p70 S6 kinase alpha (Ser447) Polyclonal Antibody at dilution of 1:1000
Phospho-p70 S6 kinase alpha (S447) Polyclonal Antibody
E-AB-20959
Protein IDP23443
Product group Proteins / Signaling Molecules
Overview
- SupplierElabscience
- Product NamePhospho-p70 S6 kinase alpha (S447) Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierWB,IHC,ELISA
- CertificationResearch Use Only
- Concentration1 mg/ml
- Protein IDP23443
- Protein NameRibosomal protein S6 kinase beta-1
- Scientific DescriptionP70 S6 Kinase alpha is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases and contains 2 non-identical kinase catalytic domains. It phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein is activated by serine/threonine phosphorylation and protein kinase C and inactivated by type 2A phosphatase. Activation leads to an increase in protein synthesis and cell proliferation. Overexpression of this kinase is involved in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
- UNSPSC12352202