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Phospho-PDCD4 (Ser457) Antibody

Research Use Only
CSB-PA785011
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPDCD4
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Cusabio
  • Product Name
    Phospho-PDCD4 (Ser457) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID27250
  • Target name
    PDCD4
  • Target description
    programmed cell death 4
  • Target synonyms
    H731; neoplastic transformation inhibitor protein; nuclear antigen H731; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ53EL6
  • Protein Name
    Programmed cell death protein 4
  • Scientific Description
    Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA Kakade D, Islam N, Maeda N, Adegoke OA (2014) BMC Cell Biol 15, 2. Wippich F, et al. (2013)Cell 152, 791-805 . LaRonde-LeBlanc N, et al. (2007)Mol Cell Biol 27, 147-56.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203