Western blot analysis of extracts from 293 cells treated with Serum using Phospho-PDCD4 (Ser457) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from 293 cells treated with Serum using Phospho-PDCD4 (Ser457) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-PDCD4 (Ser457) Antibody
CSB-PA785011
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPDCD4
Overview
- SupplierCusabio
- Product NamePhospho-PDCD4 (Ser457) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID27250
- Target namePDCD4
- Target descriptionprogrammed cell death 4
- Target synonymsH731; neoplastic transformation inhibitor protein; nuclear antigen H731; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a
- HostRabbit
- IsotypeIgG
- Protein IDQ53EL6
- Protein NameProgrammed cell death protein 4
- Scientific DescriptionInhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA Kakade D, Islam N, Maeda N, Adegoke OA (2014) BMC Cell Biol 15, 2. Wippich F, et al. (2013)Cell 152, 791-805 . LaRonde-LeBlanc N, et al. (2007)Mol Cell Biol 27, 147-56.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203