Phox-I2 [353495-22-4]

MedChem Express

Phox-I2 [353495-22-4]

10

353495-22-4

Research Use Only

99.44

C18H15N3O4

337.33

Phox-I2 is a selective inhibitor of p67phox-Rac1 interaction, binds to p67phox with high affinity with a Kd of ~150 nM. Phox-I2 is a NADPH oxidase 2 (NOX2) inhibitor and inhibits reactive oxygen species (ROS) production[1].

O=[N+]([O-])C1=CC(C2NC3=C(C4C2CC=C4)C=C(C=C3)[N+]([O-])=O)=CC=C1

-20°C,2°C to 8°C

12352200