PHOX2A antibody

GeneTex

PHOX2A antibody

9

WB: 1 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PHOX2A

paired like homeobox 2A

ARIX, CFEOM2, FEOM2, NCAM2, PMX2A, paired mesoderm homeobox protein 2A, ARIX1 homeodomain protein, aristaless homeobox homolog, aristaless homeobox protein homolog, arix homeodomain protein

Rabbit

IgG

Paired mesoderm homeobox protein 2A

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203