Phthalazinone pyrazole [880487-62-7]
HY-12564
CAS Number880487-62-7
Product group Chemicals
Estimated Purity98.0
Molecular Weight317.34
Overview
- SupplierMedChem Express
- Product NamePhthalazinone pyrazole [880487-62-7]
- Delivery Days Customer10
- CAS Number880487-62-7
- CertificationResearch Use Only
- Estimated Purity98.0
- Molecular FormulaC18H15N5O
- Molecular Weight317.34
- Scientific DescriptionPhthalazinone pyrazole is a potent, selective, and orally active inhibitor of Aurora-A kinase with an IC50 of 0.031 microM. Phthalazinone pyrazole can arrests mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells. Phthalazinone pyrazole suppresses the epithelial-mesenchymal transition (EMT) during the differentiation of hepatocyte-like cells (HLCs) from human embryonic stem cells[1][2].
- SMILESO=C1C2=CC=CC=C2C(NC3=NNC(C)=C3)=NN1C4=CC=CC=C4
- Storage Instruction2°C to 8°C
- UNSPSC12352200
![Phthalazinone pyrazole [880487-62-7]](https://www.targetmol.com/group3/M00/37/F0/CgoaEGayU_GEczepAAAAAKz-sSg041.png)