Phthalimide-PEG3-C2-OTs [382162-12-1]

MedChem Express

Phthalimide-PEG3-C2-OTs [382162-12-1]

5

382162-12-1

CHEMICAL,general_chemicals_reagents

Research Use Only

C23H27NO8S

477.53

Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG3-C2-OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

CC(C=C1)=CC=C1S(=O)(OCCOCCOCCOCCN2C(C3=C(C=CC=C3)C2=O)=O)=O

12352005