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Phytohemagglutinin [9008-97-3]

HY-N7038
MedChem Express
CAS Number9008-97-3
Product group Chemicals
Estimated Purity80.00
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Phytohemagglutinin [9008-97-3]
  • Delivery Days Customer
    5
  • CAS Number
    9008-97-3
  • Certification
    Research Use Only
  • Estimated Purity
    80.00
  • Scientific Description
    Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-kappaB, COX2, IL-1beta[1][2][3][4].
  • SMILES
    [Phytohemagglutinin]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200