PI-1840
HY-12286
CAS Number1401223-22-0
Product group Chemicals
Estimated Purity98.78
Molecular Weight394.47
Overview
- SupplierMedChem Express
- Product NamePI-1840 [1401223-22-0]
- Delivery Days Customer10
- CAS Number1401223-22-0
- CertificationResearch Use Only
- Estimated Purity98.78
- Molecular FormulaC22H26N4O3
- Molecular Weight394.47
- Scientific DescriptionPI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC50 value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of proteasome substrates p27, Bax, and IkappaB-alpha[1][2].
- SMILESO=C(N(C(C)C)CC1=NC(C2=CC=CN=C2)=NO1)COC3=CC=C(CCC)C=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200