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ProductsBack/PI3K/Akt/mTOR-IN-2 [2757804-89-8]
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CgoaEWY7ODWEZ03nAAAAALazkXo984.png
CgoaEWY7ODWEZ03nAAAAALazkXo984.png

PI3K/Akt/mTOR-IN-2 [2757804-89-8]

Research Use Only
T60564
TargetMol Chemicals
Estimated Purity99.61%
DownloadMSDS
Product group Chemicals
Molecular Weight285.29
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PI3K/Akt/mTOR-IN-2 [2757804-89-8]
  • Delivery Days Customer
    9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PI3K/Akt/mTOR-IN-2
  • Estimated Purity
    99.61%
  • Molecular Formula
    C17H13F2NO
  • Molecular Weight
    285.29
  • Scientific Description
    PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor with anticancer effects and selectivity for MDA-MB-231 cells (IC50 2.29 microM). It induces cell cycle arrest and apoptosis in cancer cells.
  • Shelf life instruction
    3 years
  • SMILES
    Fc1cc(F)cc(c1)C1OCCc2c1[nH]c1ccccc21
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway. Qin J et al., 2021 Dec 31, Bioorg Med Chem
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