PI3K/Akt/mTOR-IN-5
HY-159517
Molecular Weight542.66
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamePI3K/Akt/mTOR-IN-5
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC30H42N2O7
- Molecular Weight542.66
- Scientific DescriptionPI3K/Akt/mTOR-IN-5 (compound D3) is a derivative of Pseudolaric Acid B (HY-N6939) with anti-tumor activity. PI3K/Akt/mTOR-IN-5 inhibits excessive proliferation of tumor cells through the PI3K/AKT/mTOR and STAT3/GPX4 pathways. PI3K/Akt/mTOR-IN-5 effectively inhibits EDU positivity, reduces colony formation, places HCT-116 cells in the S phase and G2/M phase, and induces apoptosis[1].
- SMILESO=C(C1=CC[C@@]([C@@](CC1)(OC(C)=O)[C@]2([H])[C@](/C=C/C=C(C)/C(NCCN3CCCCC3)=O)(C)O4)(CC2)C4=O)OC
- UNSPSC12352200