PI3K/mTOR Inhibitor-11

MedChem Express

PI3K/mTOR Inhibitor-11 [2845104-25-6]

10

Research Use Only

99.65

C27H21N7

443.50

PI3K/mTOR Inhibitor-11 is an orally active PI3K/mTOR inhibitor (IC50: 3.5, 4.6, and 21.3 nM for PI3Kalpha, PI3Kdelta, and mTOR). PI3K/mTOR Inhibitor-11 regulates the PI3K/AKT/mTOR signaling pathway by inhibiting the phosphorylation of AKT and S6 proteins. PI3K/mTOR Inhibitor-11 can be used in the research of cancers[1].

CC(C1=NC=C(N2C(C)=NC3=C2C4=CC(C5=CN=C(NC=C6)C6=C5)=CC=C4N=C3)C=C1)(C)C#N

2°C to 8°C

12131703