PI3K/mTOR Inhibitor-8 [2492376-85-7]
HY-146200
Overview
- SupplierMedChem Express
- Product NamePI3K/mTOR Inhibitor-8 [2492376-85-7]
- Delivery Days Customer10
- CAS Number2492376-85-7
- CertificationResearch Use Only
- Molecular FormulaC23H22N8O4S
- Molecular Weight506.54
- Scientific DescriptionPI3K/mTOR Inhibitor-8 (Compound 18b) is a PI3K and mTOR dual inhibitor with IC50 values of 0.46 nM and 12 nM against PI3Kalpha and mTOR, respectively. PI3K/mTOR Inhibitor-8 induces HCT-116 cells apoptosis and arrests cell cycle at the G1/S phase[1].
- SMILESO=C(C1=CC2=NC(C3=CN=C(N)N=C3)=NC(N4CCOCC4)=C2S1)NNC(C5=CC=C(OC)C=C5)=O
- UNSPSC12131703