PIAS1 blocking peptide

GeneTex

PIAS1 blocking peptide

9

Neutralisation/Blocking

Research Use Only

200 ug/ml

Unconjugated

PIAS1

protein inhibitor of activated STAT 1

DDXBP1, GBP, GU/RH-II, ZMIZ3, E3 SUMO-protein ligase PIAS1, AR interacting protein, DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1, DEAD/H box-binding protein 1, E3 SUMO-protein transferase PIAS1, RNA helicase II-binding protein, gu-binding protein, protein inhibitor of activated STAT protein 1, zinc finger, MIZ-type containing 3

This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq, Jul 2008]

-20°C

41116100

Human